Uzbekistan has historically been a proactive driver in strengthening ties among Turkic-speaking nations. Following a period of limited engagement, a pivotal turning point occurred in 2018 when the President of the Republic attended the 6th Summit of the Organization as a Guest of Honor. In 2019, the country ratified the Nakhchivan Agreement, officially becoming a full member of the Organization of Turkic States (OTS). Since joining, Uzbekistan has proposed 116 specific initiatives, more than half of which have already been successfully implemented. The economic impact of this strategic course is evidenced by the data: at the end of 2025, trade turnover with OTS member states increased by 9.6%, reaching $10.8 billion.

Investment cooperation also shows a steady upward trend, with 4,352 enterprises operating with capital from member states as of early 2026. The Republic of Türkiye remains a key strategic partner, with bilateral relations officially elevated to the level of a Strategic Partnership in 2017. Türkiye leads all OTS countries in the number of enterprises established in Uzbekistan, reaching 2,137 units. Investment collaboration in 2025 was characterized by the utilization of funds totaling $3.2 billion, while trade turnover during the same period amounted to $3.024 billion. Transport connectivity is exceptionally robust, with 97 scheduled weekly flights operating between the cities of both nations across eight different routes, including Istanbul and Ankara.

Kazakhstan stands as Uzbekistan's largest trading partner within the Organization, with trade turnover growing by 11.4% in 2025 to nearly $5 billion. There are 1,212 enterprises with Kazakh capital successfully operating in the republic. The transport sector demonstrates immense scale, with freight volume exceeding 22.3 million tons in 2025, the majority of which—19.6 million tons—was transported via rail networks.

The dynamics of economic relations with Kyrgyzstan are marked by the highest growth rates in trade turnover, which surged by 37.1% in 2025 to reach $1.199 billion. The parties have solidified a Comprehensive Strategic Partnership, facilitating an increase in joint ventures to 346 units. The transport sector recorded a significant rise, with total freight volume growing by 22.4% in 2025 to nearly 5.4 million tons. Export shipments across all modes of transport more than doubled, indicating deep integration of production chains.

In 2024, a fundamental Treaty on Allied Relations was signed with Azerbaijan, opening a new chapter in bilateral cooperation. Trade turnover between the countries grew by 14.6% in 2025, totaling $307.3 million. In the investment sphere, 367 enterprises with Azerbaijani capital are currently active. The logistics partnership is also strengthening, as total freight volume increased by 28.3% in 2025, supported by 14 weekly flights between the capitals.

Turkmenistan, which participates in the Organization as an observer, remains a vital partner, with trade turnover reaching $1.203 billion in 2025. The launch of the Shavat-Dashoguz joint border trade zone was a practical step toward streamlining commodity exchange. As of early 2026, 270 enterprises with Turkmen capital were functioning in Uzbekistan. In the transport sector, total cargo volume for 2025 amounted to approximately 1.785 million tons, reflecting a positive growth trend of 22.5%.

Hungary also holds observer status and is actively developing high-tech cooperation with Uzbekistan. In 2025, mutual trade grew by 41.7%, reaching $117.4 million. Although there are 20 enterprises with Hungarian capital in the republic, their projects are notable for their significant scale. These include the establishment of poultry clusters in the Syrdarya region valued at $165 million and a $59 million project for the construction of water treatment facilities in "New Tashkent."